Maggie Carrel
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Malaria Genetics


Overview

Malaria remains endemic in many countries, including the Democratic Republic of the Congo (DRC) despite decades-long and billion-dollar eradication and elimination efforts.  Utilizing data from blood taken from individuals participating in 2007 and 2013 Demographic and Health Surveys in the DRC we can answer questions about how malaria moves across the landscape, if there are barriers to diffusion among malaria parasites, if malaria genetics are similar across international boundaries and where and when drug resistance emerges.

Genetics of Malaria in the DRC

Carrel, M., Patel, J., Taylor, S., Janko, M., Mwandagalirwa, M., Tshefu, A., Escalante, A., et al., (2015) The geography of malaria genetics in the Democratic Republic of Congo: a complex and fragmented landscape.  Social Science & Medicine. 133: 233-241. 10.1016/j.socscimed.2014.10.037.

Ongoing NIH and NSF funded projects, in collaboration with UNC-Chapel Hill, use dried bloodspots to determine malaria prevalence in the DRC as well as the underlying patterns and processes of genetic change in malarial parasites.
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